EPINEPHRINE 1:10,000 / 1:1,000 (ADRENALINE)

EPINEPHRINE 1:10,000 / 1:1,000 (ADRENALINE)
Class
 
  • Sympathetic agent.
Action
 
  • A potent alpha and beta stimulant that increases heart rate, cardiac contractile force, myocardial electrical activity, systemic vascular resistance, blood pressure and automaticity.
Indications
 
  • Cardiac arrest.
  • Severe anaphylaxis.
  • Bronchial asthma, croup and bronchiolitis
Contraindications
 
  • Hypertension.
  • Pre-existing tachydysrthymias with a pulse.
Precaution
  • Use with caution in pregnant patients.
  • Do not mix with sodium bicarbonate as this deactivates the epinephrine.
Side effects
  • Tachydysrhythmias.
  • Hypertension.
  • Headache.
  • Nervousness.
  • Induce early labor in pregnant women.
Administration
Rout: IV/IO Onset: <2 minutes Peak effect: <5 minutes Duration: 5-10 minutes
Rout: IM/SC Onset: 3-10 minutes Peak effect: 20 minutes Duration: 20-30 minutes
Rout: Neb Onset: Immediate Peak effect: >10 minutes Duration: <2 hours
Adult Dose:
  • Cardiac Arrest ( 1: 10,000)
    • 1 mg IV/IO push repeat every 3 - 5 minutes until ROSC or termination of efforts.
    • 1:1,000 - 2.0 mg in 8 cc normal saline ETT every 3 - 5 minutes.
  • Severe Anaphylaxis (1: 1,000)
    • 0.3-0.5mg SC/ IM
    • Repeat in 5 minutes if No improvement.
  • Severe Asthma: (1:1,000)
    • 1:1,000 - 0.3 mg SC
  • Nebulized (1:1,000)
    • 2mg in 2 ml NS Nebulized
  • For profound Bradycardia or Hypotension: 2-10 mcg per minute infusion;
    • titrate to patient response.
Pediatric Dose:
  • Cardiac Arrest (1: 10,000)
    • 0.01 mg/kg IV/IO push repeat every 3 - 5 minutes until ROSC or termination of efforts.
  • Bradycardia (1: 10,000)
    • 0.01 mg/kg IV/IO.
    • Repeat every 3 - 5 minutes as needed
  • Severe Anaphylaxis / Asthma (1: 1,000)
    • 0.01 mg/kg SC/IM.
    • Maximum single dose 0.3 mg.
    • Repeat in 5 minutes if No improvement
  • Nebulized (1:1,000) in Croup
    • 2mg in 3 ml NS Nebulized
2000 - © Civil Defense and Ambulance Authority - All rights reserved

Design & Develop by  Al Tomouh IT LLC