ATROPINE SULPHATE

ATROPINE SULPHATE

ATROPINE SULPHATE
Class
	Parasympatholytic.
Action
	Blocks acetylcholine receptors. Positive chronotrope and increases AV conduction.
Indications
	Symptomatic bradycardia. AV blocks. Asystole. Organophosphate poison.
Contraindications
	Use with caution, if at all, in 2nd degree Type II and 3rd degree blocks.
Precaution
	Dose of 0.04 mg/kg should not be exceeded except in cases of Organophosphate poisonings. For ET administration, given 2 - 2.5 times the recommended IV dose.
Side effects
	Palpitations (increased cardiac workload). Pupil dilation. Dry mouth.
Administration
Rout: IV/IM	Onset: Immediate	Peak effect: 2-4 minutes	Duration: 4 hours
Adult Dose:
	for Bradycardia:1 mg bolus, repeat every 3 - 5 minutes to a maximum of 3mg. Organophosphate poisoning: 2mg IV/IO /IM to start, repeat every 5 minutes as needed until symptoms improve.
Pediatric Dose:
	Bradycardia- Only if increased vagal tone 0.02mg/kg IV/IO rapid push Minimum dose 0.1mg and maximum single dose 0.5mg. Repeat Once after 5 minutes if needed Organophosphate poisoning 0.05-0.1mg IV/IO/IM repeat every 5 minutes as needed until symptoms improve.