FENTANYL (SUBLIMAZE)

FENTANYL (SUBLIMAZE)

FENTANYL (SUBLIMAZE)
Class
	Synthetic Potent Narcotic( Fentanyl is 100 times more potent than Morphine). Analgesic
Action
	A potent analgesic that also causes some vasodilation, thus reducing myocardial oxygen demand.
Indications
	Moderate to severe pain associated with Medical or Traumatic condition Angina, Myocardial Infarction Congestive Heart Failure Acute Pulmonary Edema Burns Isolated Injuries requiring pain relief. Amputations
Contraindications
	Known allergic to Fentanyl Hemodynamic instability or shock Respiratory depression Undiagnosed abdominal pain Patient on other Psychiatric or Anti-seizure medications
Precaution
	Toxic effects of mixed drug overdose may emerge with the reversal of the benzodiazepine effects. Have Naloxone readily available in case of respiratory depression to counteract the effects of Fentanyl Vital signs must be monitored frequently Hypotension Patient suspected head Injury
Side effects
	Respiratory Depression (May occur suddenly, and more commonly in children and the elderly) Apnea Hypotension Altered Level of Consciousness Rashes Nausea, vomiting Muscle stiffness
Administration
Rout: IV/IO	Onset: Immediate	Peak effect: 3-5 minutes	Duration: 30-60 minutes
Adult Dose:
	1-2mcg/Kg, Slow IV/IO bolus Adult and children over 12 years of age: (50-100 mcg given IV /I.O or I.M) Elderly (65 years of age &>) dose should be given at 1/2 dose (e.g. 25 mcg I.V/I.O bolus SLOW) The dose can be repeated after 10 minutes and titrated to clinical effect to a maximum cumulative dose of 100mcg. Maximum dose 100 mcg
Pediatric Dose:
	1 mcg/kg SLOW IV/IO bolus Dose can be repeated after 10 minutes and titrated to clinical effect to a maximum cumulative dose of 2 mcg/kg