NITROGLYCERIN

NITROGLYCERIN

NITROGLYCERIN
Class
	Nitrate, anti-anginal.
Action
	Rapid smooth muscle relaxant causes systemic venodilation, decreasing preload, that reduces cardiac workload. Arterial vasodilation decreasing afterload. Dilates the coronary arteries, increase blood flow to the myocardium, decrease myocardial oxygen demand.
Indications
	Chest pain associated with angina and/or myocardial infarction. Congestive heart failure with acute pulmonary edema. Hypertension.
Contraindications
	Known hypersensitivity. Hypotension. Shock. Right ventricular infarction. Suspected intracranial pressure. Recent use of erectile dysfunction medications (Viagra) within the last 24 hours.
Precaution
	May cause profound hypotension and reflex tachycardia. Nitroglycerin is light sensitive and will lose potency when exposed to air.
Side effects
	Throbbing Headache, dizziness, flushing Hypotension. Nausea / Vomiting. Decreased level of consciousness.
Administration
Rout: SL	Onset: Immediate	Peak effect: 5-10 minutes	Duration: 20-30 minutes
Adult Dose:
	0.4 mg SL (tablet or spray) repeat every 5 minutes, Maximum 3 doses.
Pediatric Dose:
	Not Indicated.