PARACETAMOL

PARACETAMOL

PARACETAMOL
Class
	Analgesics, antipyretics.
Action
	Block pain impulse generation peripherally Inhibit prostaglandin synthesis in CNS
Indications
	Control of Mild - Moderate Pain Fever
Contraindications
	Hypersensitivity Severe acute liver disease
Precaution
	Chronic liver disease
Side effects
	Nausea, headache, rash Toxicity Anemia
Administration
Rout: IV	Onset: 5-10 minutes	Peak effect: 1 hour	Duration: 4-6 hours
Adult Dose:
	1g IV infusion over 15 minutes
Pediatric Dose:
	15 mg/kg IV infusion over 15 minutes (maximum dose 1g)