SODIUM BICARBONATE 8.4%

SODIUM BICARBONATE 8.4%

SODIUM BICARBONATE 8.4%
Class
	PH buffer, alkalizing agent, electrolyte supplement
Action
	Increases blood and urinary pH by releasing a bicarbonate ion, which in turn neutralizes hydrogen ion concentrations .
Indications
	Prolonged cardiac arrest. Crush syndrome. Tricyclic antidepressant (TCA) overdose.
Contraindications
	Hypocalcemia Hypokalemia Hypernatremia Severe pulmonary edema
Precaution
	Sodium Bicarbonate can cause metabolic alkalosis when administered in large quantities.
Side effects
	Metabolic alkalosis Seizures Electrolyte disturbance.
Administration
Rout: IV	Onset: Rapid	Peak effect: 1-2 minutes	Duration: 8-10 minutes
Adult Dose:
	Cardiac arrest: 1 mEq/kg (maximum dose of 50 mEq) IV bolus over 5 minutes May repeat once in 5-10 minutes, tailored to response. Crush injury/syndrome: 1mEq/kg added to 1L of normal saline, run IV wide open just prior to extrication After extrication, consider additional dose after consulting medical direction.
Pediatric Dose:
	Same as adult but infuse slowly and only if ventilations are adequate